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Established in : 1966
 

MANDATE

• To promote production of commercially viable technology by (i) testing and upscalling processes standardized on a bench scale in different national laboratories/universities., (ii) developing infrastructure and expertise for studying customer acceptance & costing & (iii) preparing project reports for the benefit of potential entrepreneurs.
• To produce and supply important biochemicals needed in biological research as a service, until these are taken up for routine production by commercial undertaking.
• To produce and supply important biochemicals needed in biological research as a service, until these are taken up for routine production by commercial undertaking.
• To help in the off-the-shelf supply of research chemicals and biochemicals, especially those required for advanced biological research, through establishment of a commercial undertaking and to feed such a commercial undertaking continuously by developing methodologies for preparing newer products.
• To upgrade the existing technologies by exploiting new developments in the field of biotechnology.
• To conduct research on indigenously available natural products (venomous, gums, etc.) with a view to isolating chemicals for research and to exploit their commercial potential.

MAIN FACILITIES

• National facility for the synthesis of oligonucleotides is already catering to the needs of Indian scientists for the synthesis of oligonucleotides of defined sequences.
• Expertise for synthesis of biologically active peptides exists at the Centre; the facility for custom-made synthesis of small peptides for research is also available.
• The Centre houses the National facility for import and distribution of enzymes and fine chemicals.

SIGNIFICANT ACHIEVEMENTS                          

• CBT has been a pioneer in the country for manufacture and supply of allergenic extracts for diagnosis and therapy for respiratory allergenic disorders.Standardization of allergenic extracts, studies of atmospheric biopollutants like pollen and fungi in indoor and outdoor environments, and on agents causing extrinsic hypersensitivity, pneumonitis, etc are being actively pursued.The Centre has gone a long way in developing new methods for safe immunotherapy using liposomes.
• CBT has developed chemical, immuno-chemical and enzymic kits for use in clinical diagnosis. An immuno-chemical kit for the early diagnosis of aspergillosis is ready for commercialization.
• Expertise has been developed in gene synthesis and expression of proteins in E.coli. The present thrust is on the development of recombinant DNA products. Work on yeast expression system is also being pursued.
• The centre has  established a National facility for synthesis of oligonucleotides. It is supplying oligonucleotides of defined sequences to the workers in molecular biology.
• Expertise for the preparation of Fmoc and Boc protected amino acids required for peptide synthesis has been developed, and  the Centre can now supply custom made peptides.
• Methodology has been developed for large-scale isolation of phospolipids and glycosphingolipids and other biochemicals, and methods have been standardized for production of new biochemicals such as lectins, enzymes, substrates and other biologically important reagents.
• CBT is recognized as  a test laboratory by the department of Envionment and Forests for testing samples related to environmental pollution. It has also developed a testing facility for PCP content in leather which neede to be checked for leather exports.
• A microbial composition (BIO SEED) has been developed for reproducible Biochemical Oxygen Demand (BOD) analysis. It reduces the possibilities of error and makes BOD analysis easy, clean and convenient laboratory test. BOD SEED will help in determining the level of water pollution.
• A dry-reagent  type of Biostrip has been developed for qualitative  and semi-qualitative estimation of glucose in urine.It is based on development of different shades of color depending on glucose concentration present in urine. The color developed can be compared with the color chart and thereby glucose concentration can be estimated.

DIRECTOR
Dr. S. K. Brahmachari

CONTACT ADDRESS
Delhi 110 007.
Telephone: (091)11 7257471. 
Telegram : BIOCENTRE, DELHI.
Telex    : 031-78085 CFB-IN.
Fax      : (091)11-7257471.
E-mail   : cfb @sirnetd.ernet.in.